Drugmakers are racing to develop a vaccine and treatment for the pandemic, which has killed over 60,000 people since the coronavirus first emerged in China in December.
Plasma, the fluid in blood teeming with antibodies post-illness, has already proven effective in small studies to treat infectious diseases including Ebola and SARS.
The French trials are to start on Tuesday, according to a joint statement from the Paris hospital authority AP-HP, the national medical research institute INSERM, and the national blood service EFS.
“This clinical trial involves the transfusion of plasma from patients who have recovered from COVID-19, containing antibodies against the virus, and who could transfer this immunity to a patient suffering from COVID-19,” it said.
“The plasma of the people who have recovered contains these antibodies that their organisms have developed. These antibodies could help patients in an acute stage of the disease to fight the virus.”
The trials will involve 60 patients in Paris hospitals, half of whom will receive the plasma from the persons who have recovered.
It said the first results could be known two to three weeks after the trials.
The US Food and Drug Administration has already authorised physicians to experiment with the strategy to fight the coronavirus. Tests are also being done in China.