While Manchester United celebrated a historic victory in Paris, thanks in part to a last minute penalty given after the referee consulted video replays, for PSG this defeat will feel like groundhog day.
For the third year running they fail to make the quarter-finals, after their defeat at the hands of Real Madrid a year ago and their humiliating collapse against Barcelona in 2017 after they had won the first leg 4-0. They went on to lose that second leg 6-1 in Barcelona.
That defeat, known as 'La Remontada' (the comeback) is still painful for everyone connected to the Paris club.
After another shock exit the French press on Thursday were in little mood to be sympathetic with PSG after their 3 -1 loss at home to a Manchester United team with 10 players missing.
L'Equipe, the main sports paper ran with the front page “Even Worse” (Encore Pire), suggesting the defeat to a weakened Manchester United team at home was even more embarrassing than losing 6 – 1 to Barcelona.
“Two years after the Remontada, the unthinkable happened again,” read L'Equipe.
“This time the Parisians, despite enjoying a two-goal lead cracked at the Parc des Princes,” the paper said, referring to PSG's home stadium.
— Engrossed in Football (@eifmagazine) March 7, 2019
And the local newspaper in Paris Le Parisien simply called it “an unforgivable elimination”.
“An earthquake and a new industrial accident for Paris,” read the paper saying the defeat to Manchester was “pitiful”.
— Le Parisien (@le_Parisien) March 7, 2019
And Le Figaro newspaper described the crushing defeat as a “new fiasco” for PSG saying the team were humiliated.
— Will (@princedefort83) March 7, 2019
The defeat will spark yet more soul-searching among PSG's fans and notably the Qatari owners who invested in the club in 2011 with the aim of turning the club into a European powerhouse, not the laughing stock of European football.
The questions that have been asked after each elimination over recent years will be asked once again over the coming months: 'Is it the players?', 'Is it the coach?', 'Is it the club?', 'Is it the weakness of theFrench league?', 'Is it all just bad luck'?
The answers seem harder to find than ever.
PSG's German manager Thomas Tuchel said the manner of the defeat, after they had dominated much of the game, was “perhaps impossible to analyse”.
PSG are the runaway Ligue 1 leaders, but this is the third year running in which they have gone out of the Champions League in the last 16.
“If it were a league game you would wipe your mouth and go on, but today it's horrible and cruel,” he said.
“It happens once in 100 games. We did not deserve to go out over 180 minutes, but that doesn't make it easier to deal with.”