The town of Sete, near Montpellier was drenched in red wine on Tuesday night after the contents of five huge vats of wine were spilled onto the streets.
The plonk flooded into local basements, car parks, and even some people's homes, reported the local Midi Libre newspaper.
Up to 50,000 litres of the tipple belonging to the Biron distributors were spilled, according to reports.
Emergency services were quick to the scene and had the mess cleared up in 30 minutes, the paper reported.
On Wednesday afternoon, the radical group of wine producers CRAV (Comité régional d'action viticole) claimed responsibility for the move, reported France 3.
The group has infamously carried out numerous wine-related attacks in France, irate at foreign cheap wine making its way onto the shelves of French stores and supermarkets.
Spilled wine has already made headlines this year, when French farmers in April emptied the contents of Spanish wine trucks, in a protest against falling food prices in France.