• France's news in English
 
app_header_v3
France: Common drug caused birth defects in 450 babies
Photo: AFP

France: Common drug caused birth defects in 450 babies

AFP · 24 Feb 2016, 07:14

Published: 24 Feb 2016 07:14 GMT+01:00

The report put at between 425 and 450 "the number of cases of children born alive or stillborn exposed to valproate in utero between 2006 and 2014 who have congenital defects."

The estimate for all of France was extrapolated from data obtained in the Rhone-Alpes region, it said.

Starting on March 1st, the warning for pregnant women - which is already in the notice that comes with valproate - will also be written on the box, the country's general director of health, Benoit Vallet, told AFP.

The anti-convulsion drug has been flagged for several years due to the high risk of birth defects - around ten percent - but also for increased risks of mental retardation and autism.

A European report in 2014 urged all countries on the continent to review their conditions for prescribing valproate "to minimise risks".

It also called on them to take steps to ensure the medication is not prescribed to women of child-bearing age - 15 to 49 years - or pregnant women, unless no alternative treatment for epilepsy was effective.

In France, the new report noted, the drug has also been prescribed for the treatment of bipolar disorder.

Story continues below…

Valproate has been marketed in France by pharmaceutical company Sanofi under the brand name Depakine since 1967.

Also available as a generic, the drug is sold by Sanofi in some 120 countries, the manufacturer said.

Your comments about this article

Today's headlines
'War crimes committed in Aleppo': French UN envoy
A tractor clears rubble after a government strike on rebel areas of Aleppo. Photo: Thaer Mohammed/ AFP

France's envoy to the United Nations has called for an urgent Security Council meet on the war crimes he asserts are being committed in Aleppo.

'Curse of Phantom' strikes as Paris theatre burns
Anthony Crivello and Elizabeth Loyacano in the New York production of Phantom of the Opera. Photo: Really Useful Group

The curse of Phantom of the Opera has struck with a fire at a Paris theatre threatening the musical's French debut.

Two teenage girls held in France over 'terror plot'
The girls came from the same part of Nice, near Route de Turin, as Mohamed Lahouaiej Bouhlel, who carried out the nice attacks. Photo: Jesmar/Wikimedia Commons

Two teenage girls from Nice are being held on suspicion of planning a jihadi attack.

Focus
French fighter jet deal: India 'a school of patience'
Rafale jets at an assembly hanger in Merignac, southwestern France. Photo: Jean-Pierre Muller/AFP

The less-than-supersonic sale of French Rafale fighter jets to India has highlighted the obstacles facing foreign arms firms seeking to do business with the world's biggest weapons importer.

Hollande vows to 'completely dismantle' Calais Jungle
French President Francois Hollande visiting a refugee centre in Tours. Photo: Guillaume Souvant/AFP

President Francois Hollande has bowed to right-wing pressure and stepped up pledge to combat illegal migration.

First driverless minibus goes on trial in Paris
Gilbert Gagnaire, Director General of Easy Mile, poses in front of his driverless EZ10 minibus. Photo: Eric Feferberg/AFP

The French capital's transport authority will carry out its first test of a driverless minibus on Saturday.

Feature
Room for improvement: Paris's matchbox apartments
Receptionist Ivan Lopez in his tiny "chambre de bonne". Photo: Thomas Samson/AFP

Thousands of Parisians round off a hard day's work with a trudge up six flights of stairs to a tiny, stuffy room they resignedly call home.

Former president Chirac still in hospital but wife home
Bernadette Chirac executes a deal at the French Stock Exchange on September 12. Photo: Lionel Bonaventure/AFP

Former French president Jacques Chirac remains in hospital in Paris but his wife Bernadette has now been discharged.

Pope holds multi-faith meeting with Nice victims
Pope Francis kisses a baby on arrival at his weekly audience in St Peter's Square. Photo: Vincenzo Pinto/ AFP

Pope Francis will on Saturday hold a multi-faith meeting of grieving relatives and survivors of an attack in France in July when a jihadist ploughed his truck into a crowd in Nice.

Cameron school pal appointed UK ambassador to France
Ed Llewellyn has spent time in the European Commission. Photo: Gov.uk

Ed Llewellyn attended the Eton College at the same time as former PM David Cameron, and then served as his chief of staff throughout his eleven years as Conservative leader.

Sponsored Article
Why Jordan is the ‘Different’ East
National
France's Marion Cotillard rebuffs rumours of fling with Brad Pitt
National
Eight arrested over links to Nice truck attacker
Features
Why everyone should party in a French chateau at least once
Travel
The Frenchman who hated 'Nazi-Zealand' after four-day hitch-hike fail
Culture
What's on: Ten exciting events across France in September
The 45-million year old underground shells that flavour Champagne
Features
French job speak: All the terms you need to know
'Resilient' Paris now a more appealing city than New York
National
France says it's OK to warn drivers about speed cameras
Meet Honorine, 113, the oldest person in France
Education
Grenoble named France's best city to be a student
Society
New Metro map reveals cheapest pints of beer in Paris
Business & Money
How reliant is the French economy on Paris?
Society
Here's why Parisians want to move to Bordeaux
And the 'best place to spend a weekend in Europe' is… Lyon
Analysis & Opinion
'Muslims in France must be considered ordinary citizens'
Armed guards to ride French trains from October
National
France among Europe's priciest for train travel
National
Paris set to make river bank car-free for six-month trial
Society
Bordeaux hospital ranked as best in France
National
France rolls out 'world's first' driverless buses
Society
15 things a Frenchwoman can do to feel more British
Culture
Every fact you need to know about France's 'départements'
2,730
jobs available