In 2002, voters in France decided by a 51 to 49 percent margin to accept the treaty.
But an Ifop poll conducted for Le Figaro says if the same vote were held today by people who cast ballots the first time round, the agreement would be rejected.
The poll shows 64 percent of people eligible to vote in 2002 (born before 1974) would say no to the treaty.
An even higher share, 67 percent, believe the European Union is going “more in the wrong direction” since the treaty was ratified.
The euro is targeted as a contributor to the malaise, according to Ifop’s findings.
“The single currency is a very poor recruiting agent for Europe, especially among the working classes,” Ifop’s opinion department director Jerome Fourquet told Le Figaro.fr.
The poll found 45 percent of those surveyed thought the euro was a handicap in the face of the economic crisis.
The results clashed with another survey that suggested that the French are more receptive to the euro than their neighbours in Germany.
AFP reported a poll on Monday indicating that that nearly two thirds of Germans think they would be better off if they had not swapped the deutschmark for the euro.
Some 65 percent of Germans thought their personal situation would be better if they still had the mighty deutschmark, compared to 36 percent of French who
miss the franc, according to the survey by Germany's Bertelsmann Foundation.
The Germans are also less attached to the European Union, suggested the poll, which was conducted July 3rd to 8th in both countries.
Some 49 percent of those Germans questioned said they would be personally better off if the EU did not exist, compared to 34 percent of French who said
they would be better, or much better off without the EU.
The poll, also carried out in Poland, showed only 28 percent of Poles believed they would be better without the EU.
Nevertheless, despite their apparent scepticism about the euro on a personal level, 69 percent of Germans said they believed the EU was a model
for the rest of the world, compared to 56 percent of French and 59 percent of Poles.
The Bertelsmann survey was conducted by telephone among 1,001 people in Germany, 1,004 in France and 1,000 in Poland.