Depardieu was removed from an Air France flight to Dublin on Tuesday after he urinated on the floor of the aircraft just before take-off.
In an ad that ran at the weekend, Ryanair made reference to the incident to highlight its low prices.
“We’re not the only ones who piss on the competition,” says the ad, promoting the airline’s range of low cost fares.
Depardieu, one of France’s best-loved actors, told friends he was embarrassed by the incident, claiming he was caught short before take-off and had tried to urinate into a bottle.
Friends said the 62-year-old star rejected a passenger’s claim that he was drunk at the time.